Scientific Programme
The 21st Annual ENETS Conference
13 - 15 March 2024
14th Annual ENETS Postgraduate Course
Wednesday, 13 March 2024
REGISTRATION & COFFEE
Time: Wednesday 08:00 - 08:45
Room: Entrance Hall
Welcome and opening – 21st Annual ENETS Conference
Time: Wednesday 08:45 - 08:50
Room: Hall E
Opening & overview – 14th Annual ENETS Postgraduate Course
Time: Wednesday 08:50 - 09:00
Room: Hall E
Session A: Follow-up after R0 resection of thoracic and digestive NET
Time: Wednesday 09:00 - 10:30
Room: Hall E
| 09:00 - 09:15 | Recurrence free survival of thoracic and digestive NET: What we know about type and frequency
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| 09:15 - 09:20 | Q & A
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| 09:20 - 09:35 | Performance of PET imaging to detect recurrence: State of the art
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| 09:35 - 09:40 | Q & A
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| 09:40 - 09:55 | Functioning syndrome: Is it a good marker of recurrence?
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| 09:55 - 10:00 | Q & A
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| 10:00 - 10:30 | Panel discussion
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COFFEE BREAK
Time: Wednesday 10:30 - 11:00
Room: Entrance Hall
Session B: Imaging session for NET – A guide for clinicians
Time: Wednesday 11:00 - 12:30
Room: Hall E
| 11:00 - 11:15 | Feature of primary, node and liver mets of digestive NET at CT or MRI at diagnosis and treatment alteration
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| 11:15 - 11:20 | Q & A
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| 11:20 - 11:35 | Features of bone mets at CT or MRI at diagnosis and treatment alteration
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| 11:35 - 11:40 | Q & A
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| 11:40 - 11:50 | Pathological aspects
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| 11:50 - 11:55 | Q & A
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| How do I select unresectable NET patients for PRRT: The good, the bad, the unknown | (11:55 - 12:10) |
| 11:55 - 12:00 | Oncologist's view
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| 12:00 - 12:05 | Endocrinologist's view
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| 12:05 - 12:10 | Gastroenterologist's view
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| 12:10 - 12:30 | Panel discussion
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LUNCH BREAK
Time: Wednesday 12:30 - 14:00
Room: Entrance Hall
Poster presentation – Clinical science
Time: Wednesday 13:00 - 13:45
Room: Hall E
Poster presentation – Basic and translational science
Time: Wednesday 13:00 - 13:45
Room: Hall F
Session C: Does epidemiology affect the care of NEN patients?
Time: Wednesday 14:00 - 15:30
Room: Hall E
| 14:00 - 14:15 | Are NET over diagnosed? Which consequence on clinical practice?
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| 14:15 - 14:30 | Environmental factors – How do these influence preventional care?
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| Management of incidentalomas across thoracic and digestive NET primaries – Are we consistent? | (14:30 - 15:00) |
| 14:30 - 14:45 | Gastroenterologist's view
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| 14:45 - 15:00 | Surgeon's view
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| 15:00 - 15:30 | Panel discussion
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COFFEE BREAK
Time: Wednesday 15:30 - 16:00
Room: Entrance Hall
Session D: MDT – Select the best locoregional therapy in slowly progressive NETs
Time: Wednesday 16:00 - 17:30
Room: Hall E
| 16:00 - 16:08 | Case 1: Liver mets
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| 16:08 - 16:25 | MDT panel discussion
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| 16:25 - 16:33 | Case 2: Bone mets
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| 16:33 - 16:50 | MDT panel discussion
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| 16:50 - 16:58 | Case 3: Ablation of small incidental pancreatic primary
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| 16:58 - 17:15 | MDT Panel discussion
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| Summary from locoregional panel | (17:15 - 17:30) |
| 17:15 - 17:20 | Surgeon's view
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| 17:20 - 17:25 | Interventional radiologist's view
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| 17:25 - 17:30 | Radiotherapist's view
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Closing comments – 14th Annual ENETS Postgraduate Course
Time: Wednesday 17:30 - 17:40
Room: Hall E
ENETS projects
Time: Wednesday 17:40 - 18:00
Room: Hall E
2nd ENETS Basic and Translational NET Research – A Forum on Basic and Translational Science in Neuroendocrine Neoplasms
Wednesday, 13 March 2024
REGISTRATION & COFFEE
Time: Wednesday 08:00 - 08:45
Room: Entrance Hall
Welcome and opening – 21st Annual ENETS Conference (livestream from Hall E)
Time: Wednesday 08:45 - 08:50
Room: Hall F
Welcome – 2nd ENETS basic and translational NET research forum
Time: Wednesday 08:50 - 09:00
Room: Hall F
Session 1: Cells of origin in NENs
Time: Wednesday 09:00 - 10:30
Room: Hall F
| 09:00 - 09:15 | Cells of origin in PanNENs
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| 09:15 - 09:30 | Cells of origin in gastric NENs
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| 09:30 - 09:45 | Cells of origin in lung NENs
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| 09:45 - 10:10 | Panel discussion
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| 10:10 - 10:17 | Abstract Presentation 1
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| 10:17 - 10:20 | Discussion
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| 10:20 - 10:27 | Abstract Presentation 2
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| 10:27 - 10:30 | Discussion
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COFFEE BREAK
Time: Wednesday 10:30 - 11:00
Room: Entrance Hall
Session 2: Immune tumor microenvironment and opportunities for therapy in NENs
Time: Wednesday 11:00 - 12:30
Room: Hall F
| 11:00 - 11:15 | The road from nSARS-CoV-2 vaccines to therapeutic vaccines against cancer: Where are we?
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| 11:15 - 11:30 | Adoptive cellular therapies and innovative immunotherapeutic approaches against NENs
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| 11:30 - 11:45 | The roles of extracellular vesicles in the immune system
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| 11:45 - 12:00 | Panel discussion
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| 12:00 - 12:07 | Abstract Presentation 3
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| 12:07 - 12:10 | Discussion
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| 12:10 - 12:17 | Abstract Presentation 4
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| 12:17 - 12:20 | Discussion
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| 12:20 - 12:27 | Abstract Presentation 5
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| 12:27 - 12:30 | Discussion
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LUNCH BREAK
Time: Wednesday 12:30 - 14:00
Room: Entrance Hall
Session 3: DAXX/ATRX and MEN1 role in NET tumorigenesis
Time: Wednesday 14:00 - 15:30
Room: Hall F
| 14:00 - 14:10 | DAXX/ATRX and MEN1 function in healthy tissues
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| 14:10 - 14:25 | Oncogenic mechanisms associated with DAXX/ATRX and MEN1 alterations in NETs and what we still do not understand
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| 14:25 - 14:40 | Clinical impact of DAXX/ATRX alterations in NETs: A two-faced role
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| 14:40 - 15:00 | Panel discussion
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| 15:00 - 15:07 | Abstract Presentation 6
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| 15:07 - 15:10 | Discussion
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| 15:10 - 15:17 | Abstract Presentation 7
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| 15:17 - 15:20 | Discussion
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| 15:20 - 15:27 | Abstract Presentation 8
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| 15:27 - 15:30 | Discussion
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COFFEE BREAK
Time: Wednesday 15:30 - 16:00
Room: Entrance Hall
Session 4: Biology of PRRT
Time: Wednesday 16:00 - 17:35
Room: Hall F
| 16:00 - 16:15 | PRRT mechanisms of action: Known and unknown
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| 16:15 - 16:30 | How can we advance PRRT, new preclinical model?
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| 16:30 - 16:45 | Red marrow toxicities of PRRT: Biological mechanisms
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| 16:45 - 17:05 | Panel discussion
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| 17:05 - 17:12 | Abstract Presentation 9
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| 17:12 - 17:15 | Discussion
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| 17:15 - 17:22 | Abstract Presentation 10
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| 17:22 - 17:25 | Discussion
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| 17:25 - 17:35 | Conclusive remarks
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Closing comments – 2nd ENETS basic and translational NET research forum
Time: Wednesday 17:35 - 17:40
Room: Hall F
21st Annual ENETS Conference
Wednesday, 13 March 2024
Welcome reception
Time: Wednesday 18:00 - 19:00
Room: Entrance Hall
Thursday, 14 March 2024
Satellite Symposium - Industry-sponsored
Time: Thursday 07:45 - 08:45
Room: Hall F
Session 1: Interdisciplinary management of neuroendocrine tumor syndromes – Which tools for which goals?
Time: Thursday 09:00 - 10:30
Room: Hall E
| 09:00 - 09:20 | Keynote speech: MEN-1 – State of the art
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| 09:20 - 09:30 | Molecular approaches for the diagnosis of hereditary NEN in 2023 – The geneticist view
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| 09:30 - 09:40 | MEN-2-3-4
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| 09:40 - 09:45 | Discussion
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| 09:45 - 09:55 | von Hippel Lindau disease
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| 09:55 - 10:00 | Discussion
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| 10:00 - 10:10 | Inherited small intestinal NET
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| 10:10 - 10:15 | Discussion
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| 10:15 - 10:22 | Abstract Presentation 11
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| 10:22 - 10:25 | Discussion
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| 10:25 - 10:30 | Final comments & Wrap-up
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COFFEE BREAK
Time: Thursday 10:30 - 11:00
Room: Entrance Hall
Session 2A: Drug development in NENs: Where are we heading?
Time: Thursday 11:00 - 12:30
Room: Hall E
| 11:00 - 11:10 | Development of SST-targeted drugs: Current and future perspectives
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| 11:10 - 11:15 | Discussion
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| 11:15 - 11:25 | Update on clinical trials with systemic therapies in NETs
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| 11:25 - 11:30 | Discussion
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| 11:30 - 11:40 | Update on clinical trials with systemic therapies in NECs
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| 11:40 - 11:45 | Discussion
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| 11:45 - 11:55 | What can we achieve with molecular profiling of NENs and when should it be done?
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| 11:55 - 12:00 | Discussion
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| 12:00 - 12:10 | T-Cell redirecting strategies in NENs: CARs, BiTEs and beyond
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| 12:10 - 12:15 | Discussion
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| 12:15 - 12:22 | Abstract Presentation 12
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| 12:22 - 12:25 | Discussion
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| 12:25 - 12:30 | Final comments
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Session 2B: Clinical science abstract session
Time: Thursday 11:00 - 12:10
Room: Hall F
| 11:00 - 11:07 | Abstract Presentation 13
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| 11:07 - 11:10 | Discussion
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| 11:10 - 11:17 | Abstract Presentation 14
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| 11:17 - 11:20 | Discussion
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| 11:20 - 11:27 | Abstract Presentation 15
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| 11:27 - 11:30 | Discussion
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| 11:30 - 11:37 | Abstract Presentation 16
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| 11:37 - 11:40 | Discussion
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| 11:40 - 11:47 | Abstract Presentation 17
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| 11:47 - 11:50 | Discussion
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| 11:50 - 11:57 | Abstract Presentation 18
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| 11:57 - 12:00 | Discussion
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| 12:00 - 12:07 | Abstract Presentation 19
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| 12:07 - 12:10 | Discussion
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LUNCH BREAK
Time: Thursday 12:30 - 14:00
Room: Entrance Hall
Satellite Symposium - Industry-sponsored
Time: Thursday 12:30 - 14:00
Room: Hall F
Session 3A: Joint ENETS/ESMO session
Time: Thursday 14:00 - 15:10
Room: Hall E
Understanding biology to improve patient care
| 14:00 - 14:15 | ...in NETs
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| 14:15 - 14:20 | Discussion
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| 14:20 - 14:35 | ...in NECs
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| 14:35 - 14:40 | Discussion
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| 14:40 - 14:55 | ESMO / ENETS GEP NEN guidelines/guidance: Clinical application
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| 14:55 - 15:00 | Discussion
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| 15:00 - 15:07 | Abstract Presentation 20
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| 15:07 - 15:10 | Discussion
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Session 3B: Basic and translational science abstract session
Time: Thursday 14:00 - 15:00
Room: Hall F
| 14:00 - 14:07 | Abstract Presentation 21
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| 14:07 - 14:10 | Discussion
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| 14:10 - 14:17 | Abstract Presentation 22
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| 14:17 - 14:20 | Discussion
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| 14:20 - 14:27 | Abstract Presentation 23
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| 14:27 - 14:30 | Discussion
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| 14:30 - 14:37 | Abstract Presentation 24
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| 14:37 - 14:40 | Discussion
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| 14:40 - 14:47 | Abstract Presentation 25
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| 14:47 - 14:50 | Discussion
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| 14:50 - 14:57 | Abstract Presentation 26
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| 14:57 - 15:00 | Discussion
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Life Achievement Award
Time: Thursday 15:10 - 15:30
Room: Hall E
| 15:10 - 15:20 | Laudatio
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| 15:20 - 15:30 | Recipient and keynote address
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COFFEE BREAK
Time: Thursday 15:30 - 16:00
Room: Entrance Hall
Session 4A: Push the former limits – Rising endoscopic and surgical techniques for the treatment of GEP-NETs
Time: Thursday 16:00 - 17:30
Room: Hall E
| 16:00 - 16:10 | Endoscopic treatment of gastroduodenal NETs – Techniques and limits
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| 16:10 - 16:15 | Discussion
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| 16:15 - 16:25 | Endoscopic ablation of small pNEN – Techniques and limits
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| 16:25 - 16:30 | Discussion
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| 16:30 - 16:40 | Resection of advanced neuroendocrine liver metastases – New options and limits
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| 16:40 - 16:45 | Discussion
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| 16:45 - 16:55 | Vascular resections for locally advanced pNETs – Techniques and limits
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| 16:55 - 17:00 | Discussion
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| 17:00 - 17:10 | Resection of locally advanced SI-NET – Techniques and limits
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| 17:10 - 17:15 | Discussion
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| 17:15 - 17:22 | Abstract Presentation 27
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| 17:22 - 17:25 | Discussion
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| 17:25 - 17:30 | Closing comments
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Session 4B: Nurse and dietitian symposium
Time: Thursday 16:00 - 17:30
Room: Hall F
Roundtable Discussion: Barriers to access high-quality care in NENs
Time: Thursday 17:45 - 18:45
Room: Hall E
| 17:45 - 18:00 | EU NEN Policy Recommendations (Take-home messages)
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| 18:00 - 18:45 | Roundtable discussion – Physicians', patients' & politicians' perspectives
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- Physician’s perspective from different geographic regions
- Patient’s perspective (INCA representative)
- Politician’s perspective (EU Commissioner representative)
Friday, 15 March 2024
Satellite Symposium - Industry-sponsored
Time: Friday 07:45 - 08:45
Room: Hall F
Session 5A: Targeted radionuclide therapy – Recent advances
Time: Friday 09:00 - 10:30
Room: Hall E
| 09:00 - 09:15 | PRRT with 177Lu labelled somatostatin analogues: Current status and future directions
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| 09:15 - 09:20 | Discussion
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| 09:20 - 09:35 | Targeted alpha radionuclide therapies – A game changers?
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| 09:35 - 09:40 | Discussion
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| 09:40 - 09:55 | What is next – New isotopes and novel targets?
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| 09:55 - 10:00 | Discussion
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| 10:00 - 10:07 | Abstract Presentation 28
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| 10:07 - 10:10 | Discussion
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| 10:10 - 10:17 | Abstract Presentation 29
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| 10:17 - 10:20 | Discussion
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| 10:20 - 10:27 | Abstract Presentation 30
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| 10:27 - 10:30 | Discussion
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Session 5B: INCA/ENETS
Time: Friday 09:00 - 10:30
Room: Hall F
| 09:00 - 09:05 | Opening
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| 09:05 - 09:20 | Think NENs – Educating primary care physicians about NENs
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| 09:30 - 09:35 | Think NENs video collage and a demo of the e-learning platform
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| 09:35 - 09:42 | Promoting Think NENs locally and globally
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| 09:42 - 09:50 | Key to success and lessons learned
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| 09:50 - 10:05 | Engaging second-line non-NEN healthcare professionals
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| 10:05 - 10:10 | Working as a global community to promote better understanding of NENs
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| 10:10 - 10:27 | Discussion
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| 10:27 - 10:30 | Wrap-up and closing comments
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COFFEE BREAK
Time: Friday 10:30 - 11:00
Room: Entrance Hall
Session 6: Best NET publications – What's new in the field?
Time: Friday 11:00 - 12:15
Room: Hall E
| 11:00 - 11:25 | Basic science
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| 11:25 - 11:50 | Translational science
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| 11:50 - 12:15 | Clinical science
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Awards Ceremony
Time: Friday 12:15 - 12:35
Room: Hall E
Closing comments
Time: Friday 12:35 - 12:50
Room: Hall E
LUNCH BREAK
Time: Friday 12:50 - 14:00
Room: Entrance Hall