Scientific Programme
1st World NET Forum
Took place as a Hybrid Event on 8 - 9 March 2022
in Barcelona, Spain
Programme
8 - 9 March 2022 - Hybrid Event
Tuesday, 08 March 2022
Welcome
Time: Tuesday 11:00 - 11:10
Marianne Pavel, GER /
Session 1: Models in NET research
Time: Tuesday 11:10 - 12:20
Chairs:
Jie Chen, CHN /
Anne Couvelard, FRA /
Simron Singh, CAN /
11:10 - 11:40
Keynote address: An organoid biobank of neuroendocrine neoplasms enables genotype-phenotype mapping
Kenta Kawasaki, JPN /
11:40 - 12:00
Talk 1: State-of-the-art NET tumor models: Present & future
Dawn Quelle, USA /
12:00 - 12:20
Discussion
Coffee break
Time: Tuesday 12:20 - 12:50
Session 2: NET tumor biology advances
Time: Tuesday 12:50 - 14:45
Chairs:
Emily Bergsland, USA /
Aurel Perren, SUI /
12:50 - 13:20
Keynote address: Understanding tumor biology of NEN by integrated genomic analysis
Aldo Scarpa, ITA /
13:20 - 13:30
Discussion
13:30 - 13:45
Talk 1: Epigenetic control of human intestinal neuroendocrine cell differentiation
Ramesh Shivdasani, USA /
13:45 - 13:55
Discussion
13:55 - 14:10
Talk 2: Immune and stromal heterogeneity associated with cellular origin and cancer evolution in GEP-NET
Anguraj Sadanandam, GBR /
14:10 - 14:20
Discussion
14:20 - 14:35
Talk 3: Mechanisms of RB loss in neuroendocrine carcinoma
Nancy Joseph, USA /
14:35 - 14:45
Discussion
Summary of sessions 1 & 2
Time: Tuesday 14:45 - 15:00
Justo P. Castaño, ESP /
Coffee break
Time: Tuesday 15:00 - 15:30
Oral abstract presentations - Part I
Time: Tuesday 15:30 - 16:55
Chairs:
Hironobu Sasano, JPN /
Ramesh Shivdasani, USA /
15:30 - 15:40
Characterising aggressive pulmonary carcinoids through integrative omics analysis
Alexandra Sexton-Oates, FRA /
15:40 - 15:50
Discussion
15:50 - 16:00
Broncho-pulmonary combined large-cell neuroendocrine carcinomas (Co-LCNEC): More than a hybrid neoplasm
Michele Simbolo, ITA /
16:00 - 16:10
Discussion
16:10 - 16:20
Molecular, histopathological, and functional characterization of the dysregulation of the splicing machinery in lung carcinoids
Víctor García Vioque, ESP /
16:20 - 16:30
Discussion
16:30 - 16:40
Comprehensive transcriptomic and methylomic analysis of NENs from multiple origins show subgroups of patients with clinical relevance
Carlos Carretero, ESP /
16:40 - 16:50
Discussion
16:50 - 16:55
Summary - Part I
Coffee break
Time: Tuesday 16:55 - 17:15
Oral abstract presentations - Part II
Time: Tuesday 17:15 - 19:00
Chairs:
Douglas Hanahan, SUI /
Eva Tiensuu Janson, SWE /
17:15 - 17:25
Molecular deciphering of primary liver neuroendocrine neoplasms confirms its distinct existence with foregut-like profile
Louis de Mestier, FRA /
17:25 - 17:35
Discussion
17:35 - 17:45
Epigenetic ageing and metabolic traits of multi-focal ileal neuroendocrine tumors
Amy Webster, GBR /
17:45 - 17:55
Discussion
17:55 - 18:05
Tumor neoantigens shape the immune microenvironment of panNETs: An in silico analysis
Mauro Cives, ITA /
18:05 - 18:15
Discussion
18:15 - 18:25
Epigenetic progression steps in alpha-lineage MEN1-DAXX/ATRX mutated Pancreatic Neuroendocrine Tumors (PanNET)
Ilaria Marinoni, SUI /
18:25 - 18:35
Discussion
18:35 - 18:45
Novel patient-derived tumor organoid models reveal growth-factor dependencies in neuroendocrine tumors and serve as a platform for neuroendocrine cancer research
Talya Dayton, NED /
18:45 - 18:55
Discussion
18:55 - 19:00
Summary - Part II
Wednesday, 09 March 2022
Welcome
Time: Wednesday 11:00 - 11:10
Session 3: Therapeutic advances in NET
Time: Wednesday 11:10 - 12:40
Chairs:
Bertram Wiedenmann, GER /
Hong Zhao, CHN /
11:10 - 11:40
Keynote address: Deciphering NET tumor invasiveness to potentiate real therapy candidates
Douglas Hanahan, SUI /
11:40 - 11:50
Discussion
11:50 - 12:05
Talk 1: From genomics to functional genomics: The discovery and targeting of ATRX and MEN1 mutations in PanNETs
Yuchen Jiao, CHN /
12:05 - 12:15
Discussion
12:15 - 12:30
Talk 2: Mechanisms of resistance to PRRT and overcoming these
Rod Hicks, AUS /
12:30 - 12:40
Discussion
Coffee break
Time: Wednesday 12:40 - 13:10
Session 4: Novel areas in NET diagnostic and therapy
Time: Wednesday 13:10 - 14:40
Chairs:
B.A. Krishna, IND /
Kjell Öberg, SWE /
Hironobu Sasano, JPN /
13:10 - 13:40
Keynote address: Precision oncological approach in neuroendocrine tumors (lessons from NET and other cancers)
Andrea Califano, USA /
13:40 - 13:50
Discussion
13:50 - 14:05
Talk 1: New radionuclides for improved diagnosis and therapy in NET
Cristina Müller, SUI /
14:05 - 14:15
Discussion
14:15 - 14:30
Talk 2: CAR-T cell technology
Xianxin Hua, USA /
14:30 - 14:40
Discussion
Summary of the day
Time: Wednesday 14:40 - 14:55
Marianne Pavel, GER /
Closing comments
Time: Wednesday 14:55 - 15:05
Marianne Pavel, GER /